How Does Maeng Da Kratom Works For Pain Management?

Maeng Da Kratom has been the most crucial Kratom strain for the management of pain. Many people who suffer from chronic pain usually take this strain of Kratom, but they aren’t aware of proper dosing or how to take it. The reason being the FDA hasn’t approved it yet for pain management, so there is no appropriate guideline available.

However, in this article, we will delve more into the working mechanism of Maeng Da as an analgesic substance, its dosage, its side effects, and how to take it.

Maeng Da Kratom and pain management

We are already aware that Maeng Da Kratom is one of the many strains of Kratom that is famous for its analgesic and stimulation properties. The many different alkaloids present in Maeng Da are responsible for its analgesic properties. Let’s have a look at these alkaloids and how they act on various receptors to alleviate pain;

  • Mitragynine: It has the main activity on the μ receptors in the brain that promotes analgesia. However, it is the same receptor that may cause physical dependence, so you need to avoid overdoing it.
  • 7-Hydroxymitragyine: This alkaloid is present in abundance in the Maeng Da strain, and it has a potency 13 times greater than morphine and 46 times greater than Mitragynine. It has quick-acting characteristics and is responsible for antinociceptive action, which deactivates the signals from nociceptors (nerve endings in the body that detect pain). This alkaloid has better penetration through the blood-brain barrier, thus greater bioavailability. 

These two alkaloids are also known for activating noradrenergic and serotonergic pathways down the spinal cord, thus adding up to the analgesic effect.

However, bear in mind that none of these findings were concluded on human clinical based studies. All these results were brought forward after research was done on animals.

What is the dosage of Maeng Da for pain management?

Scientific research says that Maeng Da Kratom or any other strain of Kratom if taken in low to moderate doses, around 1-5 grams produce a mild stimulant effect that is pleasant and not as intense as the effects produced by amphetamine-like drugs. At this dosage, you will typically also start feeling the analgesic effects.

Users review that they like the stimulant effects associated with painkilling effects more than the sedative effects which occur when one takes massive doses, i.e., 10-15 grams of Kratom. Some users report that at very high doses of Maeng Da Kratom, they start feeling an unpleasant sense of anxiety and internal agitation. Higher doses also produce euphoric effects.

Reports from Kratom users suggest that a moderate dose of Maeng Da Kratom is enough to produce analgesia, and this is somewhere between 5-15 grams of raw leaves. For Maeng Da Kratom Powder, a dose of 7-8 grams is enough to produce analgesia.

However, I recommend that you take small doses initially to identify your sweet spot. Do not increase your dose immediately; do it gradually. Be patient; you will get your desired effects.

How to take Maeng Da Kratom for pain?

Maeng Da Kratom can be taken in many forms such as;

  • Capsules
  • Powder
  • Extract
  • Tincture

These are the different forms of Maeng Da Kratom available in the market. You can take any of these Maeng Da types. The extract and tincture form is more robust and concentrated versions of the strain, so with them, you need to be cautious about the dosing.

The capsules can be taken quickly. Depending on the dose that you are taking for your pain management, choose the right amount before a meal. This way, the absorption of Kratom is not delayed. If you are taking it in the powder form that you can be a little creative. Add the Maeng Da Powder to your morning coffee or take it with a milkshake to get rid of the bitter taste.

Avoid taking large doses, as it might sedate you. Also, do not take one strain of Kratom for long periods. Keep changing the strain and do not consume it daily.

If you would like to potentiate the effects of Maeng Da Kratom, you can take it with grapefruit juice. Please do not take it with any drugs and stimulants or other painkillers.

User reviews of Maeng Da for pain

I recently got this review of Maeng Da Kratom in my inbox, which I found worth sharing.

“It’s been almost a year now, that I am at peace, I am happier. I got into a car accident three years back that badly deformed my spine and underwent six surgeries in 2 years. I know the struggle of waking up every day not able to walk, and as the day passed, feeling that excruciating pain is searing across your spine, suffocating you, not letting you even breathe. Morphine ran in my veins as I struggled to keep my pieces together, till I couldn’t. I gave up. The surgeries helped me enough that I restored my toe movements only. And now that I knew I had to live without being able to walk ever, I wanted a pain-free life. And luckily, in those desperate moments of searching and scrolling on the internet for hours, I came across your Kratom website. I had tried everything, even had Morphine addiction, wanted to give it a try knowing I had nothing else to lose. I placed my order and got it two days later. It was a year back on this very day I started my Kratom journey for the management of my pain, and here I am a survivor, and not just that, a happy survivor, who manages her day, who doesn’t cry anymore, who is putting an effort to collect her pieces again. Thank you, Kratom!”


Maeng Da Kratom is a potent analgesic, and the trick lies in moderate safe dosing to have maximum effects of the strain. If you are someone who is dealing with conditions having chronic pain, then Kratom can effectively help you.

However, if you are taking any medications for your health condition, you shall not take Kratom as it can lead to adverse drug interactions. Therefore, take Kratom responsibly and share your Kratom stories with us.

Frequently Asked Questions

What are the other benefits of Maeng Da?

Maeng Da is a potent stimulant that boosts your energy levels and enables you to work better. It increases your focus, as well as your attention span. It has a positive role in your cognition. Maeng Da Kratom also helps in the alleviation of anxiety, reduces stress, and can act as an antidepressant as it elevates mood. At high doses, Maeng Da acts as a sedative and helps with sleeping disorders like insomnia and parasomnia.

What are the side effects of Maeng Da?

Like all the other strains of Kratom, Maeng Da is a safe Kratom when not take in a combination. It may result in mild side effects like;
·        Nausea
·         Vomiting
·         Constipation
·         Stomach upset
·         Dry mouth
·         Dizziness at high doses
·         Anxiety and agitation at high doses

If you experience any of these side effects, please stop taking Maeng Da and report to your doctor. Please avoid taking Maeng Da Kratom with any other stimulants like amphetamines, Opiates, etc.

What other strains of Kratom can I take for the management of my pain?

1. Bali Kratom: The Red Bali Kratom has a high content of 7-hydroxymitragynine, and therefore, it is one of the most potent strains of Kratom when it comes to analgesia. The duration of action of this strain lasts up to 7 hours. Medium to moderate doses of this strain is effective in alleviating chronic pain.
2. Malay Kratom: Super Green Malay Kratom is an effective Kratom strain for the management of mild pain and inflammation. The effects last for up to 8 hours. If pain is affecting your productivity, you may take this strain of Kratom.

Can I mix Maeng Da with Opiates?

We strongly contraindicate the combination of Opiates and Maeng Da Kratom as it can lead to adverse outcomes. These include severe respiratory depression, followed by coma and death. Please avoid taking Kratom with any CNS depressants like alcohol or stimulants like Nicotine, Morphine, Amphetamine, and Opiates.

Can I take Maeng Da if I have a Fatty Liver?

No, you cannot. The metabolism of Kratom takes place in the liver, and if you have any liver disease, please avoid taking any strain of Kratom. If you have any other co-morbid, especially those related to cardiovascular and renal disorders, please do not consume Kratom. Always consult your doctor before taking Kratom in such conditions.

What is a strong Maeng Da dose?

Generally, as described above, you can take Maeng Da in a dose of 5-15 grams for analgesia. Any dose greater than 15-20 grams is too much and must not be taken.

How can I figure out an accurate dose for myself, and when does Maeng Da kick in?

Although it is tricky, you don’t need to worry. Get yourself a weighing scale if you are using Kratom powder and start by taking 2 grams of Maeng Da. The effects will appear around 30 minutes later. If the results don’t appear, don’t get disappointed. After a day or two, take a dose of 3 grams and see if it works for you. Do not take repeated doses in the same day to achieve effects as it might cause adverse side effects. Gradually build your dosage to have optimal outcomes.

How can I avoid tolerance?

This is simple. Avoid taking large doses of Maeng Da regularly. If you do so, you will build a tolerance to a specific dose of Maeng Da and will need a higher dose to achieve the effects. Give it a break and have completely clean periods of days to weeks where you aren’t taking any Kratom products.

How shall I rotate Kratom strains?

It would help if you had a couple of Kratom strains at hand to practice the rotation of Kratom. This is a useful method to avoid dependence and building tolerance. To make you understand better, have a look at this example;
On Monday, if you take Maeng Da Kratom, go for a relatively less potent strain on Tuesday, like Red Malay Kratom, and take a different strain on Wednesday. On Thursday, you may go back to Maeng Da. This is how you rotate Kratom.

Low Dose vs. High Dose Maeng Da

At low doses of Maeng Da, users report that they have stimulating effects, mood elevation, and a mild euphoria with analgesic effects.
At high doses of Maeng Da, one feels exceptionally euphoric and goes into a relaxed state, drifting slowly into sleep. Users report sedative effects at high doses.

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Andrew Coria is the main partner at SNB and a dedicated Warrior in the fight for Kratom. He has served thousands of customers during his work in the industry and yet still thinks of himself as a customer as well. His work has been featured on popular kratom blogs such as Kratom Guides and Red Storm Scientific actively discussing trending botanical topics in the industry. Andrew works only with highly vetted farmers whom he trusts to make quality their #1 factor for the customer. His expertise is practiced by providing the cleanest products on the market, backed by industry-standard lab testing.


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